Anti-cancerous effects of graviola have been demonstrated in various vitro studies, and because of its traditional usage it is touted as cancer fighting herbal supplement. Graviola's leaves, bark, seeds and fruit possess various health promoting properties that can be helpful for variety of health concerns. Graviola contains many active compounds and chemicals which have numerous healing properties; one of them is natural phytochemicals known as annonaceous acetogenins which is the main focus of researchers. Some researches have confirmed that annonaceous acetogenins has potent anti-tumor properties and exhibit selective toxic property against tumor cells. Other clinical studies also demonstrated the powerful anticancerous, antitumorous, and antiviral properties of annonaceous acetogenins.
Recent studies have found that natural compounds of graviola, acetogenins have superb property to inhibit the enzyme processes that are specifically present in membrane of cancerous cells. Through this mechanism of action they are toxic for cancerous cells and don't create toxicity in healthy cells. Purdue University published a promising news in 1997, that Annonaceous acetogenins are not only effective in destroying tumor cells but also have ability to show resistance to anti-cancer agents and appear to have a unique affinity for such resistant cells.
National Cancer Institute has been also explored the toxic effects of graviola against cancerous cells in its plant screening program in 1976. In this plant screening program, it is illustrated that graviola stem and leaves demonstrated active toxic effects against cancer cells. In various vitro clinical trials, it has been studied that specific phytochemical acetogenins that are found in graviola herb, have been shown their selective toxic effects against various cancerous cells like lung carcinoma cell lines, prostate adenocarcinoma, breast tumor lines, liver cancer cell lines, pancreatic carcinoma cell lines, colon adenocarcinoma cell lines and multi-drug resistant breast adenocarcinoma. Other clinical findings conducted by scientists of Taiwan suggested that at very low dosages, annonaceous acetogenins of graviola exhibited highly toxic effects particularly to ovarian, breast, cervical, bladder and skin cancer cell lines.
Along with the antitumourous effects of graviola, it is also discovered that the compound annonaceous acetogenins which are found in graviola herb, also exhibit antiparasitic, insecticidal, and antimicrobial activities. The graviola (Annona muricata) leaves possess antioxidant potential and play a role as an effective radical scavenger and augments its therapeutic effects. Another clinical study on graviola also suggests that alkaloids present in graviola fruit showed antidepressants effects in animals.
Graviola cancer cure is still under investigation, but it is clearly inspiring that it is used world widely for its potential to cure serious ailments. Graviola extracts, Graviola powder other and Graviola supplements are easily available to promote optimal health and can be taken as general health tonic. But still further detailed researchers are needed to be conducted on graviola to prove that graviola is an ultimate cancer cure.
